Also indexed as: 2-dimethylaminoethanol, Dimethylaminoethanol
What is DMAE? DMAE (2-dimethylaminoethanol) is a chemical produced in the brain.
Like choline, DMAE may increase levels of the brain neurotransmitter acetylcholine; however, not all studies confirm that DMAE serves as a precursor to acetylcholine.Early preliminary research suggested that DMAE may relieve the symptoms of tardive dyskinesia (a trembling disorder caused by long-term anti-psychotic medication), but several controlled studies did not find the effects of DMAE better than placebo. In fact, one case report suggested that DMAE can cause symptoms of tardive dyskinesia.
One small, uncontrolled four-week trial of senile patients given DMAE supplements of 600 mg three times per day, failed to show any changes in memory but did produce positive behavior changes in some of the patients. However, subsequent double-blind research did not find a significant benefit from the use of DMAE in people with Alzheimer’s disease.
Where is DMAE found? DMAE is a naturally occurring chemical compound related to choline. It is found in fish. Salmon sardines and anchovies are particularly rich in DMAE.
DMAE (2-dimethylaminoethanol) may increase levels of the brain neurotransmitter acetylcholine. In one preliminary trial, people with senile dementia were given DMAE supplements of 600 mg three times per day for four weeks. The participants did not show any changes in memory, though some did show positive behavior changes. However, a subsequent double-blind trial found no significant benefit from DMAE supplementation in people with Alzheimer’s disease.
Tardive dyskinesia Dimethylaminoethanol (DMAE) is a natural choline precursor. Although some preliminary data suggested that DMAE could decrease TD symptoms,16 most studies show that DMAE is no more effective than placebo for TD.
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